In Vitro Sensitization Assays

Non-animal Toxicology Testing

MB Research - In Vitro Sensitization Assays

In Vitro Sensitization Testing

Genomic Allergen Rapid Detection System

  • in vitro test method for dermal sensitization based on gene expression analysis of stimulated models of Dendritic cells
  • GARDskin, GARDpotency, & GARDair

Direct Peptide Reactivity Assay (DPRA)

  • Accepted in vitro assay for dermal sensitization screening by ECVAM
  • Measures molecular reaction of specific peptides to possible sensitizers

In Vitro Sensitization Screening Assay (IVSA)

  • Using the 3D Reconstructed Human Epidermis protocol currently under review by ECVAM
  • Measures IL18 production in epidermal keratinocytes
  • For more information, see IVSA.

Human Cell Line Activation Test (h-CLAT)

  • Examines dendritic cell activation by quantifying changes in the expression of cell surface markers (CD86 and CD54) in the human leukemia cell line THP-1
AOP-sensitization
Over 45yrs Experience in Toxicology Testing

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